Complete inhibition of leukemia cell line


1: J Nat Prod. 2003 Aug;66(8):1124-7. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, Iinuma M, Nozawa Y. Gifu International Institute of Biotechnology, 1-1 Naka-Fudogaoka, Kakamigahara, Gifu 504-0838, Japan. This email address is being protected from spambots. You need JavaScript enabled to view it.
PMID: 12932141 [PubMed - indexed for MEDLINE]


mangosteen-01We examined the effects of six xanthones from the pericarps of mangosteen, Garcinia mangostana, on the cell growth inhibition of human leukemia cell line HL60.

All xanthones displayed growth inhibitory effects. Among them, alpha-mangostin showed complete inhibition at 10 microM through the induction of apoptosis.
Disclaimer
The Xanthones from the mangosteen have been shown in laboratory studies to be powerful Antioxidants, Anti-Inflammatories and to have other special properties. However, laboratory results do not guarantee that the same will happen in the human body. Mangosteen is a nutritious fruit not a drug, and no therapeutic claims are made for this product.